Programme

Day 1: Thursday, September 3rd, 2026

TimeLocation: Exhibition Space ARC Engage, 237ABC
14:00Welcome ECR networking
15:00Registration
15:30Keynote – Brian Bender (Isomorphic Labs) and Andrew Brown/Maria Waldhoer (Ikherma)
16:30Poster & Sponsor Flash Talks – Early Career Researchers
18:00GPCR Network Ceilidh (GUU Debates Chamber)

Day 2: Friday, September 4th, 2026

TimeLocation: Exhibition Space ARC Engage, 237ABC
09:00Breakfast
Session 1 – Context-specific GPCR signalling
09:30Maria Shchepinova (University of Bath) – Proximity proteomics approaches to resolve GPCR interactomes
09:50Emily Russell (BioAscent) – Context‑dependent pharmacology of 5‑HT₂ receptors – implications for Drug Discovery
10:10Maria Marti-Solano (University of Cambridge) – Reconstructing GPCR signalling networks to uncover cell-specific rewiring and new pathway to phenotype relationships
10:30Bianca Plouffe (Queen’s University of Belfast) – When Membranes Decide: Lipid Control of GPCR Signalling Specificity
10:50-11:10Coffee break
Session 2 – Structural insights into GPCRs
11:10Isabella Russell (AstraZeneca) – Cryo-EM structures of constitutively active PTH1R mutants
11:30George Hedger (Imperial College London) – Subcellular lipid modulation of mitochondrial GPCRs
11:50Satya Bhamidimarri (Domainex) – From Native Membranes to Drug Discovery: Stabilizing Native GPCRs in Polymer Nanodiscs​
12:10Peter McCormick (University of Liverpool) – TBC
12:30-14:30Lunch break
13:00-14:00Poster Session Judging (Exhibition Space ARC Engage Lobby)
Session 3 – GPCR function in Physiology and Disease
14:30Caroline Gorvin (University of Birmingham) – MMRAP2: an accessory for appetite regulation
14:50Rob Lane (University of Nottingham) – Targeted inhibition of mu-opioid receptors in neuronal subpopulations by membrane-tethered Naloxo-DART antagonists
15:10Stuart Mundell (University of Bristol) – Inverse agonism at platelet G protein-coupled receptors in patients with acute coronary syndromes
15:30Brian Hudson (University of Glasgow) – Physiological FFA4 Free Fatty Acid Receptor Signalling in 3D Cultured Adipocytes
16:00Closing remarks & Prizes

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